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Le Dôme occupies one floor of the five-storey Dôme building at Roissy Charles de Gaulle International Airport, north east of Paris. This is France's main passenger airport and Europe's busiest for cargo. The Dôme, built in 1993, is made up of eight office blocks linked by a glass atrium, providing plenty of natural light. It is part of the Roissypôle complex of office buildings, shops and hotels within the airport perimeter.

The centre shares the Dôme with air freight and other service providers, including Air France. There is a shuttle to the terminals and frequent high speed train (TGV) and suburban rail services into Paris, other parts of France and Belgium. The centre has parking and is convenient for major road routes.